What will the drug industry look like in 20 years? Can we get there? How?
 FROM LEFT: DON SAWYER, TONY FOUGEROLLES, JOE SHIELDS (CENTER AND RIGHT BY JOHN HALPERN)
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These questions keep pharma folks up at night, especially those at the top, where 20-th century strategies and short-term
solutions tno longer fit the bill. Reasons for panic are plenty, whether you're staring down a small biotech's ever-shortening
runway or a big pharma's fast-approaching patent cliff. Of course, it's hard times in every industry these days, but none
has anywhere near the inherent contradictions and high risks, regulations, technologies, and costs pressing down on every
aspect of its business. True innovation in this maze is a near miracle.
But that's what it will take—true innovation, not the buzzword, but the real thing—and Pharm Exec's 2009 27 Emerging Leaders
know it and are striving for it. That may be why slightly more than a third hail from biotech. And nine of our honorees have
already made such strides so fast that it seemed only fair to single them out. Four are MD/PhDs leading high risk/reward R&D
efforts, while the other five (two are MDs) are meeting huge business challenges with a scientist's openness to the unexpected.
All of our Emerging Leaders are under age 45, and their first decade or two in pharma has left them with few illusions about
the many near-miracles that will be required for enduring success. Yet they remain confident. We hope their their clear-eyed,
sometimes sharp-tongued assessment of what must (and must not) be done to create a pharma for the 21st century will prove
inspiring—and then give you a good night's sleep. The 2009 Emerging Leaders are:
Mohan Bangalore, Wyeth
Carrolee Barlow, Braincells, Inc.
Hans Bishop, Bayer Healthcare
Stephanie Bova, Pfizer
Virginia Carden Carnahan, Vertex Pharmaceuticals
Andrew Cheng, Gilead Sciences
Scott Cormack,Oncogenex Pharmaceuticals
Craig Dashefsky,Schering-Plough
Michelle
Dipp,
GlaxoSmithKline
Antonin (Tony) de Fougerolles,
Alnylam
Jean-Marc Huet,
Bristol-Myers Squibb
Blair Jackson,
Alkermes
Frank Karbe,
Exelixis
Joe Mclane,
Merck
Kathryn Metcalfe,
Pfizer
C. Randall Mills,
Osiris Therapeutics
Paulash Mohsen,
Pfizer
Elizabeth Mutisya,
Solvay Pharmaceuticals
Stefan Platz,
Roche
Jason Rhodes,
Alnylam
Luca Santarelli,
Roche
Don Sawyer,
Astrazeneca
Joe Shields,
Wyeth
Jennifer Spear Smith,
Wyeth
Jeffrey Tong,
Infinity Pharmaceuticals
Julia Walker,
Astrazeneca
Ceci Zak,
Sanofi-Aventis US