Articles by L.J. Sellers - Pharmaceutical Executive

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Articles by L.J. Sellers

It's All About Immunity

Hollis-Eden is developing drugs that help the body fight foreign attackers —including radiation.
May 1, 2005

In a non-human primate study, high doses of Neumune resulted in 90 percent survival against a lethal level of radiation.

Bold Bets

Serono is muscling its way into the US market with head-to-head trials and big marketing partners.
Jan 1, 2005

From its origins as a small company making reproductive hormones to its current status as market leader in multiple sclerosis, Serono has always done things in a big way. The company created the infertility market with two early products: Pergonal (menotropins), used for the in vitro fertilization (IVF) of the first test-tube baby, and Profasi (chorionic gonadatropin), collected from the urine of 100,000 postmenopausal women. Serono later boldly put its MS drug Rebif (interferon beta1a) up against Biogen's Avonex, a similar interferon, in a head-to-head trial and proved Rebif's superiority.

Feeling No Pain

Endo is nicely poised to grab a big piece of the rapidly expanding pain-management market.
Nov 1, 2004

Lifecycle management and line extensions helped the Percocet franchise generate steady annual growth, rising from $40 million in 1997 sales to $214 million in 2003, despite the fact that it had no patent protection.

Synta's Surprise

A small molecule for autoimmune diseases? No one expected that.
Sep 1, 2004

Synta is in a very unusual position: Two Big Pharmas have paved the way with proteins, while the small biotech follows with a pill.

Cholesterol Champions

The scientists who developed Lipitor are once again making history in the war on plaque.
Aug 1, 2004

We had a vision that this project deserved a company with a focus on HDL as the next frontier in the cardiovascular area.

Virus Hunter

Gilead goes after big game.
Jun 1, 2004

Of all disease agents, viruses are the most challenging prey. They are crafty bits of genetic material that penetrate healthy cells and manipulate them into making more virus. The scientists who hunt them must be equally stealthy: Search and destroy does not work. And in this game, scientists cannot really boast of conquest, they must settle for simply holding their opponent at bay. To accomplish even that, the deadly human immunodeficiency virus (HIV), which affects an estimated 40 million people worldwide, must be attacked daily in three different ways.

Pharm Exec 50

Pharmaceutical Executive ranks the top 50 pharma companies
May 1, 2004

Last year, pharma sold $466 billion in Rx drugs. Here are the companies driving industry's growth.

Special Delivery

Nektar Therapeutics began with a small focus on inhaled proteins, then recently expanded its technology base and list of Big Pharma partners.
Apr 1, 2004

Nektar—the drug delivery firm formerly know as Inhale—has been around for 14 years, but its pace during the last few has been dizzying. In 2001, the company made two major acquisitions that not only expanded its technology base from inhaled therapeutics to a broad range of exciting new technologies, but also gave it revenue from five products on the US market that use its technology and lined-up another four in Phase III. In 2002, Nektar brokered 11 collaborative partnerships, and in 2003, it generated $106 million in sales.

Better Drugs Through Diagnostics

CeMines hopes to improve cancer drugs by developing a screening test that helps determine the right therapy.
Feb 1, 2004

The genomics revolution may not have ushered in the age of personalized medicine the way healthcare experts predicted, but innovative diagnostics keep pushing the industry toward the ideal of the "right drug for the right person at the right time. "One company that exemplifies that model is CeMines, a Colorado-based enterprise with an impressive, noninvasive cancer diagnostic in development. The product, which uses molecular fingerprinting to test blood samples, has had a 100 percent accuracy rate for every trial conducted. It not only determines-even in early stages-if a patient has cancer, but provides guidance for which type of treatment will work best.

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