The First Dose Is Everything: Improving Adherence and Persistence with Noble SureStartRx™

The first dose of a self-injectable therapy is a critical moment that often determines whether patients move forward with treatment or abandon it due to uncertainty. Noble’s SureStartRx™ program addresses this challenge by sending remote demonstration kits through specialty pharmacies, allowing patients to practice injections and build confidence before their first dose. Research shows that when demonstration kits are added to standard support, patients initiate therapy sooner, adhere better in the short term, and stay on treatment longer. In this discussion, Noble’s Director of Patient Engagement Services, Sean Glynn, explains how improving patient confidence at the start of therapy can protect both patient outcomes and long-term brand value.