
“AI as Reinvention”: Transforming the Business of Medicine
Sanofi Chief Digital Officer Emmanuel Frenehard on scaling AI across a Big Pharma global enterprise and why a strategy of concentrated AI bets — not scattered pilots — can better drive real transformation without losing sight of governance, culture or patients.
In this video episode of the Pharm Exec podcast, Emmanuel Frenehard, executive vice president and chief digital officer at Sanofi, shares how the company is embedding artificial intelligence throughout research, clinical development, manufacturing, commercial operations and the employee experience.
Joining Mike Christel, group managing editor, MJH Life Sciences, Frenehard details Sanofi's three-tiered AI strategy — snackable, specialized and generative — and why he believes AI's real power lies in reinventing workflows rather than simply automating them.
Other highlights include:
- From pilots to AI-native: Why workforce upskilling, focused investment and deep organizational commitment are what distinguish companies successfully scaling AI.
- Product-lifecycle impact: Learn how AI can reshape molecule discovery, clinical trial simulation, biologics manufacturing, supply chain resilience and commercial engagement to help improve speed and patient outcomes.
- Responsible AI in health care: Frenehard discusses Sanofi's governance framework, AI oversight board and “human-in-the-loop” approach to ensuring trust and transparency. “AI without governance runs the risk of becoming chaos,” he notes.
- Building the AI workforce of the future: Sanofi’s evolving global AI centers of excellence; cultivating curiosity, collaboration and continuous learning; and drawing from lessons in the consumer tech world, the leadership principles and talent strategy necessary to drive long-term digital transformation in pharma.
Click below to listen to the audio version and subscribe to the Pharmaceutical Executive Podcast:




