Pharmaceutical Executive Daily: Pfizer's Stock Drops Following 2026 Revenue Projections Release

Welcome to Pharmaceutical Executive Daily, your quick briefing on the top news shaping the pharmaceutical and life sciences industry.

In today’s Pharmaceutical Executive Daily, Pfizer discloses its 2026 revenue expectations, a bipartisan group of House Republicans moves to force a vote on extending ACA tax credits, and new collaboration and merger activity highlights continued dealmaking momentum across biopharma.

Pfizer’s stock moved lower after the company reduced its full-year 2026 revenue projections, citing ongoing portfolio adjustments and longer-term pressures following the COVID-era revenue decline. The updated guidance underscores the challenges large biopharma companies face as they rebalance pipelines, manage patent cliffs, and reset investor expectations.

On the policy front, four Republican lawmakers have broken ranks with House GOP leadership to push for a vote on extending Affordable Care Act tax credits. The move highlights growing internal divisions around healthcare affordability and could have implications for coverage stability, payer dynamics, and downstream access considerations for pharmaceutical manufacturers.

In deal news, Harbor BioMed announced a collaboration and license agreement with Bristol Myers Squibb, while VYNE Therapeutics entered a merger agreement with Yarrow Bioscience. The transactions reflect continued strategic partnering and consolidation as companies look to strengthen pipelines and optimize development portfolios.

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