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In this short video, some of the leading figures in the pharma industry talk disruption and transformation-Brexit, US pricing pressures, and the rise of ultra-expensive gene and cell therapies-all subjects to be explored in more depth at this year's FT Pharmaceutical and Biotech Conference on November 11-12 in London. Longer individual interviews can be seen on the FT Live channel's playlist. Further information about the conference, visit live.ft.com/pharmabio