AstraZeneca is the stock to beat in the United Kingdom.

The global pharmaceutical company saw its stock rise to its all-time high this week, Reuters reports.¹ The news outlet also reports that the surge makes it the largest UK-listed stock by market value.

How high did AstraZeneca's stock rise?

The stock rose to 134.6 pounds, giving the company a value of about 210 billin pounds.

The news comes after the company issued its quarterly earnings report last week.

In a statement on the company’s website,² AstraZeneca chief executive officer Pascal Soriot commented on positive news in the earnings report. He said, “The strong underlying momentum across our business through the first nine months of the year sets us up well to sustain growth through 2026 and has us on track to deliver our 2030 ambition.”

He continued, “Across our pipeline we have announced an unprecedented 16 positive Phase III trials this year, with four since our previous results including high-impact readouts for baxdrostat in hypertension and Enhertu and Datroway in breast cancer. We are also delivering on our strategy to strengthen our operations in the United States to power our growth. This includes a historic agreement with the US government to lower the cost of medicines for American patients, and broadening our US manufacturing footprint having broken ground at our new $4.5bn Virginia manufacturing facility in October."

The news also follows to major announcements for AstraZeneca’s footprint in the US market. First, the company announced plans in early October to increase its investment in its Virginia manufacturing facility to $4.5 billion, which it says will create 3,600 new jobs in the region.³

At the time of announcement, Soriot said, “With our $4.5 billion investment in Virginia, the largest in AstraZeneca’s history, we are not only building a state-of-the-art manufacturing facility, but also driving life sciences innovation and economic growth. This new facility will create thousands of jobs and strengthen America’s national security and health sovereignty. I also want to thank Governor Youngkin and his team for their energy and vision. We have found in Virginia an amazing team that moves at incredible speed to build a better future for this Commonwealth and the American people.”

Virginia Governor Glenn Youngkin also commented on the deal, saying, “AstraZeneca’s $4.5 billion investment is the largest in the company’s history and a game-changer for American drug manufacturing. The investment is set to create 3,600 jobs in Virginia, strengthening America’s ability to produce life-saving medicines. Thanks to programs like the Virginia Business Ready Sites Program and the Virginia Talent Accelerator Program, AstraZeneca is going to be able to hit the ground running. That means better jobs, better medicine, and better opportunities for the people of Virginia.”

A few days later, AstraZeneca announced that it had struck a deal with the Trump Administration to reduce the cost of medications.⁴ The deal also included the announcement of an additional $50 billion investment in domestic sourcing.

At the time, Soriot said, “Every year AstraZeneca treats millions of Americans living with cancer and chronic diseases and, as a result of today’s agreement, many patients will access life-changing medicines at lower prices. This new approach also helps safeguard America’s pioneering role as a global powerhouse in innovation and developing the next generation of medicines. It is now essential other wealthy countries step up their contribution to fund innovation.”

Source

1. AstraZeneca hits record high, cements lead as UK's biggest stock. Reuters. November 11, 2025. https://www.reuters.com/business/healthcare-pharmaceuticals/astrazeneca-hits-record-high-cements-lead-uks-biggest-stock-2025-11-11/
2. 9M and Q3 2025 results. AstraZeneca. November 6, 2025. Accessed November 11, 2025. https://www.astrazeneca.com/media-centre/press-releases/2025/9m-and-q3-2025-results.html
3. AstraZeneca plans to increase investment and scope of its Virginia manufacturing facility to $4.5 billion, creating 3,600 new jobs. AstraZeneca. October 9, 2025. Accessed November 11, 2025. https://www.astrazeneca.com/media-centre/press-releases/2025/astrazeneca-plans-to-increase-investment-and-scope-of-its-virginia-manufacturing-facility-to-dollar45-billion-creating-3600-new-jobs.html
4. AstraZeneca announces historic agreement with US Government to lower the cost of medicines for American patients. AstraZeneca. October 10, 2025. Accessed November 11, 2025. https://www.astrazeneca.com/media-centre/press-releases/2025/astrazeneca-announces-historic-agreement-with-us-government-to-lower-the-cost-of-medicines-for-american-patients.html