Feature|Videos|July 16, 2025

The Ins and Outs of Value-Based Contracts: Timing, Evidence, and Risk Alignment

Industry experts react to the developer’s role in preparing for value-based contracting, acknowledging that innovative agreements can support access when evidence is still maturing.

There is no shortcut to executing a value-based contract. In this episode, experts lay out what’s required to bring these agreements to life: evidence alignment, data compatibility, and mutual incentive. Payers want results, not just risk transference—and developers must understand and speak to payer business goals.

Key discussion topics include:

  • Timeline and prerequisites for executing value-based contracts.
  • Understanding what matters to payers vs. regulators.
  • How to prototype contracting models for early feedback.
  • The importance of strong head-to-head clinical data as the foundation.

Related to this article

Dr Martine Dehlinger-Kremer
Earlier pediatric planning, innovative trial design, and closer collaboration among regulators, industry, and families are needed to close the persistent gap between the evidence available for adult and pediatric treatments.